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Table 1 Common, rare and total number of variants identified by LASSO, SPLS and by both methods.

From: Gene-based analysis of rare and common variants to determine association with blood pressure

  

Common variants

 

Rare variants

 

Combined variants

Trait

Region

A

B

C

D

Region

A

B

C

D

Region

A

B

C

D

SBP

LAMP3

167

28

21

2

TP63

485

109

94

31

LAMP3

267

18

21

2

 

LIMD1

371

20

39

15

     

LIMD1

538

88

39

18

           

RAP2B

15

1

1

1

DBP

Inter-530

315

72

104

29

BAP1

24

7

8

7

BAP1

30

8

9

8

 

CTDSPL

277

20

19

14

Inter-378

42

10

10

7

CCCDC66

373

42

57

20

 

SLC25A36

88

7

6

6

Inter-896

23

4

8

4

Inter-376

10

1

2

1

      

Inter-898

55

8

14

8

Inter-377

41

5

8

4

      

CPB1

52

3

7

2

Inter-378

75

11

10

7

      

DNAH1

211

40

41

16

Inter-896

47

4

8

4

      

E1F5A2

34

11

5

5

Inter-982

206

27

2

2

      

GLYCTK

13

4

5

4

CPB1

164

18

9

5

      

NCBP2

24

2

2

2

DNAH1

326

114

43

31

      

SEMA3G

30

7

8

5

EIF5A2

77

19

5

5

      

TNNC1

7

3

4

3

GLYCTK

25

4

5

4

      

WDR82

36

11

12

10

PHF7

40

3

14

3

           

PIGZ

115

5

6

5

           

PPM1M

12

2

2

2

           

SEMA3G

42

7

8

5

           

TNNC1

10

3

4

3

           

TWF2

50

10

10

9

           

WDR82

73

11

12

10

MAP

LAMP3

167

20

2

2

     

GP5

32

6

2

2

 

LIMD1

371

10

51

5

     

LAMP3

267

3

2

2

           

LIMD1

538

49

106

35

           

RAP28

15

2

2

1

  1. A, number of total variants; B, number of variants selected by LASSO; C, number of variants selected by SPLS; D, number of variants selected by both LASSO and SPLS; Inter-376, region between PPMIM & WDR82; Inter-377, region between WDR82 & GLYCTK; Inter-378, region between GLYCTK & DNAH1; Inter-530, region between NXPE3 & LOC152225; Inter-896, region between RPL22L1 & EIF5A2; Inter-898, region between SLC2A2 & TNIK; Inter-982, region between ST6GAL1 & RPL39L
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BMC Proceedings

ISSN: 1753-6561

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